Researchers provided subjects with a supplement containing glucosamine and collagen.
Compared to the placebo group, these subjects demonstrated an increase in disc volume and a reversal in some metrics of disc degenerative changes.
Conclusions
Glucosamine and collagen supplements can have beneficial effects at preventing and in some cases reversing degenerative changes to the spine associated with injury or aging.
Reference
Laky, B., Huemer, D., Eigenschink, M., Sagl, B., Thell, R., Wagner, K. H., … & Heuberer, P. R. (2024). A Dietary Supplement in the Management of Patients with Lumbar Osteochondrosis: A Randomized, Double-Blinded, Placebo-Controlled Study. Nutrients, 16(16), 2695.